Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis. – PubMed

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A double-blind, placebo-controlled, randomized trial was carried out with the aim of proving efficacy of standardized balm mint cream [active ingredient: 1% Lo-701–dried extract from Melissa officinalis L. Herpes esophagitis is a viral infection of the esophagus caused by the herpes simplex virus type 1 (HSV-1). Previous in vitro and in vivo studies indicated that catechins from the tea plant (Camellia sinensis) have a therapeutic effect on herpes simplex virus infections. Koytchev’s study7 was a randomized, double-blind controlled trial (RDBCT) of LomaherpanTM, a proprietary 1% cream of a lyophilized aqueous extract.3 The cream was applied daily for five days and compared to a placebo of identical vehicle. After primary orofacial infection with the herpes simplex virus (type 1, HSV-1), up to 40% of HSV seropositive subjects suffer recurrent herpes infections which are characterized by painful erosions of the involved skin mainly around the lips (herpes labialis). Koytchev’s study7 was a randomized, double-blinded controlled trial of Lomaherpan™, a proprietary 1% cream of a lyophilized aqueous extract.3 The cream was applied qd for five days and compared to a placebo of identical vehicle. Oral herpes is an infection caused by the herpes simplex virus.

Symptoms of the herpes virus vary depending on whether the outbreak is initial or recurrent. A range of topical and systemic therapies exists for treating recurrent herpes labialis. The “moving wall” represents the time period between the last issue available in JSTOR and the most recently published issue of a journal. Proportion of subjects in whom the primary lesion complex does not progress beyond the Papule/Edema Stage. Proportion of subjects in whom the primary lesion complex does not progress beyond the Papule/Edema Stage. Authors’ addresses: Rajesh Waikhom, Krishna Patil, Dipankar Sircar, Arpita Roychowdhury, Sanjoy Dasgupta, and Rajendra Pandey, Department of Nephrology, IPGMER and SSKM Hospital, Kolkata, West Bengal, India, E-mails: rajesh.waikhom{at}gmail.com, kpatil1008{at}gmail.com, deepsircar{at}gmail.com, lahiri.arpi{at}gmail.com, dasgupta.sanjay{at}rediffmail.com, and rajenpandey{at}vsnl.net. Description: Founded in 1904, The Journal of Infectious Diseases is the premier publication in the Western Hemisphere for original research on the pathogenesis, diagnosis, and treatment of infectious diseases, on the microbes that cause them, and on disorders of host immune mechanisms.

The therapy with thymus extracts, oral and parenteral, reduced the frequency and the intensity of recurrences of herpes labialis infections. The aim of this study is to determine the safety and efficacy of a topical natural health product in comparison to placebo for the treatment of herpes labialis. Consecutive blood donors at 25 sites in southern Wisconsin were interviewed in 1985 to ascertain recurrent herpes labialis histories, other perioral conditions, and status on possible predisposing factors and correlates of lesion recurrence. The purpose of this study was to ascertain how accurate the general public was at diagnosing the condition of recrudescent herpes labialis. The results of this proof-of-concept Phase IIb trial demonstrated a one and a half day (or 35 hours) reduction in the intent-to-treat population median time to healing in the active treatment group as compared to the placebo group (113 hours versus 148 hours; p= 0.02). Herpes labialis (cold sore) is an infection that appears on your lips, caused by a virus called type 1 herpes simplex virus (HSV-1), which is responsible for those painful sores on your lips. Causes The virus responsible for cold sores is the Herpes simplex virus (or HSV).

Recurrent herpes simplex labialis caused predominantly with herpes simplexvirus 1(HSV-1) is a major problem, for which various treatments have minimal impact. The purpose of this study was to ascertain the applicability of infrared thermography to study the natural history of herpes labialis lesions. N2 – Objective Previous in vitro and in vivo studies indicated that catechins from the tea plant (Camellia sinensis) have a therapeutic effect on herpes simplex virus infections. Recrudescent herpes labialis (RHL) is a disease caused by herpes simplex virus (HSV), predominantly type 1 (HSV-1). To test the safety of Xerese (acyclovir and hydrocortisone)Cream 5%/1% for the treatment of recurrent cold sores in children ages 6-11yrs after 5 days of treatment. Before a month, someone who has labial herpes kissed me on my cheek. It usually presents as a blister with liquid at the outer part of the lips or on the peri-oral area and then it “breaks”, creating a small sore, which is why it is also called “cold sore”.

Lesley-Ann L. Research and Markets has announced the addition of the “Herpes Labialis (Oral Herpes) – Pipeline Review, H1 2016” report to their offering. Population Age: Adults, Elderly Gender: Male, Female Trial protocol: IT (Completed) Trial results: (No results available) EudraCT Number: 2010-021144-17 Sponsor Protocol Number: EA10-01-998 Start Date*: 2011-01-12 Sponsor Name:Engelhard Arzneimittel GmbH & Co. Abstracts The efficiency of the Zovirax cream in the treatment of recurrent herpes labialis was studied in 30 patients with either prodromal symptoms, advanced clinical picture of the disease with erythema and vesicles with serous content or complicated by secondary infection.